Intraoperative Fluorescence Is Useful but Not Always Sufficient in Contrast-Enhancing Malignant Gliomas

Fluorescence-guided resections have become standard of care for malignant gliomas.Strong fluorescence has been shown to correlate with solid enhancing tumor.However, with experience it has also been 15-1 shampoo shown that visualized fluorescence may not identify the entire extent of the tumor.

Knowing that malignant gliomas extend beyond the contrast-enhancing tumor seen on magnetic resonance imaging (MRI), reliance only on the fluorescence intraoperatively may not be enough.Intraoperative ultrasound is a readily available tool for real-time assessment of resection status, irrespective of the tumor type.We describe one such case in which after resecting all the visible vaidehi pant fluorescing tumor component, we identified a significant component of nonfluorescing tumor, using intraoperative ultrasound that was further resected completely.

This illustrates the need for multimodal intraoperative guidance for achieving optimal tumor resection in malignant gliomas.

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